Jan–?? 1518Grijalva exploressouthern Gulf of Mexico
18 Nov 1518–22 Apr 1519Cortés leads expeditionfrom Cuba to Mexico
Dec 1518–May 1519Smallpox devastatesTaíno populationof Hispaniola
Mar 1519Cortés foundsSanta María de la Victoria
Mar 1519–Jan 1520De Pineda exploresnorthern Gulf of Mexico
22 Apr 1519Cortés foundsVilla Rica de la Vera Cruz