Oct 1500–?? 1501Bastidas exploresSouth American coastas far as Panama
1501Spanish importfirst African slavesto New World
1501First Spanishsettlement onmainland Venezuela
May 1502Failed Spanishcolony onGuajira Peninsula
May 1502–Nov 1504Columbus exploresCentral American coast
Sep 1502–Jun 1520Aztec expansionunder Moctezuma II
6 Jan–16 Apr 1503Unsuccessful Spanishsettlement in Panama